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Relationship between HOMA-IR and GLP-1

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) and GLP-1 (Glucagon-Like Peptide-1) are two important indicators related to the assessment and management of insulin resistance and glucose regulation in the body.

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance):

  • Definition: HOMA-IR is an indicator used to assess insulin resistance. This index is calculated based on blood glucose levels and fasting insulin levels.
  • What it means: A high HOMA-IR value indicates a high level of insulin resistance, which means that the body is not using insulin effectively to regulate blood glucose levels.

GLP-1 (Glucagon-Like Peptide-1):

  • Definition: GLP-1 is a hormone incretin that is secreted from the small intestine after a meal. It plays an important role in regulating glucose by stimulating insulin secretion from the beta cells of the pancreas and inhibiting glucagon secretion.
  • Function:
    • Increases insulin secretion when blood glucose levels are high.
    • Inhibits glucagon secretion, which reduces the amount of glucose produced by the liver.
    • Slows down the process of emptying the stomach, which helps reduce the rate of absorption of glucose into the bloodstream.
    • Create a feeling of fullness, help control the amount of food consumed.

Connection between HOMA-IR and GLP-1:

  1. Insulin Resistance and GLP-1:
    • When the body is resistant to insulin (high HOMA-IR), the effectiveness of insulin decreases, leading to higher blood glucose levels.
    • GLP-1 has the ability to boost insulin secretion to help lower blood glucose levels. Therefore, GLP-1 levels are often increased as a compensatory mechanism in insulin resistance to improve glucose regulation.
  2. Improving Insulin Resistance with GLP-1:
    • GLP-1 agonists (GLP-1 agonists) are used in the treatment of type 2 diabetes to improve insulin resistance and control blood glucose.
    • These drugs enhance the efficacy of natural GLP-1, thereby reducing HOMA-IR by increasing insulin secretion and reducing glucose production from the liver.
  3. Clinical Studies:
    • Numerous studies have demonstrated that the use of GLP-1 agonists can significantly improve insulin resistance and reduce HOMA-IR levels in patients with type 2 diabetes.
    • For example, in clinical studies, patients using GLP-1 agonists have shown significant reductions in HOMA-IR and improved glycemic control.

The link between HOMA-IR and GLP-1 is important in understanding and treating metabolic disorders associated with insulin resistance and type 2 diabetes. GLP-1 may play an important role in improving insulin resistance, helping to reduce HOMA-IR and support more effective blood glucose control.

Introducing Collagen GlucoTrojan from JBA Brands

Collagen GlucoTrojan from JBA Brands is the perfect combination of collagen peptides and natural essences, providing outstanding benefits to your health and skin. With its high collagen content and precious ingredients from nature, this product not only helps maintain youthfulness but also supports overall health. The product is manufactured in the US and has been listed on the FDA’s Daily Med page.


  • High Collagen Content: Each dose provides up to 8000 mg of high-quality collagen peptides.
  • Natural Ingredients: Combines essences from white strawberry leaves, young mango leaves and banana stem juice.
  • Optimal Efficiency: Carefully selected ingredients are used to ensure optimal performance for users.
  • Safe and Benign: Contains no preservatives, colorants or artificial flavors.
  • Made in the USA: Products are made in the USA, ensuring the highest quality and complying with strict FDA standards.
  • Daily Med Listed: Accredited and listed on the FDA’s Daily Med page.

Clinical Study Results:

  • Passed 2 Clinical Trials: The product has undergone 2 clinical trials in the US.
  • Reduced HOMA-IR: Clinically proven to reduce HOMA-IR (insulin resistance index) by 42% within 4 weeks, which means the product helps increase the secretion of the hormone GLP-1 in the intestines.
  • Improved Cholesterol Ratio: LDL/HDL ratio decreased by 67% and TC/HDL ratio decreased by 67%, significantly improving heart health.

Target Users:

  • People who want to maintain and improve their skin, hair, and nails.
  • People who need support to control blood sugar and promote comprehensive health.
  • People who want to look for natural, safe and effective products.

Experience the perfect combination of collagen peptides and natural essences with Collagen GlucoTrojan from JBA Brands. Bring youthful skin, superior health and natural beauty to you every day!

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